"Instead of a less invasive method, such as smoking or a tincture?"
There are many advantages to the rectal administration of cannabis not afforded by other routes. Medicine may still be administered even if the oral route is impaired (e.g., due to vomiting, an injured jaw or throat, or gastrointestinal difficulties) or disallowed due to the oral intake restrictions that are frequently required both before and after surgery. Avoiding the gastrointestinal tract also prevents first-pass metabolism by the stomach and liver, which break down many different molecules into their constituent parts (including ฮ9-tetrahydrocannabinol, otherwise known as THC), and allows the active constituents to reach the blood in much higher concentrations.
In the case of THC, the liver transforms around half of what is ingested into the significantly more psychoactive metabolite 11-Hydroxy-ฮ9-tetrahydrocannabinol. While not harmful in and of itself and potentially of therapeutic benefit, this molecule causes much more intense cognitive effects than THC. Rectal administration not only avoids these effects, but also allows a much greater proportion of THC to eventually reach the blood stream. Rectal administration also allows for medicine to exert effects over localized ailments (e.g., hemorrhoidal tissue, inflammation of the rectum, or tumors in the rectal cavity). This form of use also has a much faster uptake than oral administration (around 10 minutes, on average) and leads to more consistent blood concentrations of the active constituents.
Backdoor Medicine: How Marijuana Suppositories Can Save Lives
"You want me to put that where?!"
By Nicholas Fraleigh / Cannabis Digest March 12, 2015
drpinto
Thank you for your question. There are many benefits to using an anal suppository and when you have tried it, you might discover that it is not so invasive after all.
The bioavailability of cannabis with rectal use lies at over 60%, inhalation about 30% and oral about 20%. That means that more of the medicine can have an active effect on the body when used this way. Moreover, cannabis is processed differently when used rectally and most people do not experience a psychoactive high and can benefit from a higher THC content than otherwise, especially if a psychoactive high is not desired.
People use our suppositories rectally for many reasons: low back pain, sciatica, overall body relaxation and well-being, head aches, sleeping and more.
Another great use for especially Foria Explore is for anal play where the local effects of pain relief, pleasurable tactile enhancement and relaxation play a large role.
In conclusion, putting cannabis in your butt can be very beneficial! ๐
karin
