I have fibromyalgia and osteoarthritis. I take blood pressure meds Atenolol and lisinopril. I also have a low resting heart rate 58- 60 bpm. Will cannabis effect the effectiveness of my blood pressure needs or lower my resting heart rate. Thanks much

Hi there!
In the very short term, cannabis elevates blood pressure and heart rate. However, prolonged administration of THC, in both humans and experimental animals, results in the lowering of both blood pressure and heart rate. Animal studies suggest that this may be due to a reduction in adrenergic tone, which is also how beta-blockers, such as metoprolol, work as anti-hypertensives. 
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228270/#R11
However, cannabis will not lower blood pressure or heart rate excessively.
Hope this helps!

drkim