Prostate enlargement is mostly cause by a condition called Benign prostatic hyperplasia (BPH). Hyperplasia is an increase in cell numbers due to a normal physiological response to demand placed on a tissue. Testosterone makes your prostate grow, which can increase symptoms of benign prostate disease. Unfortunately, there are no available studies on Cannabis Sativa and it’s effect on hyperplasia or more specifically BPH. However, studies suggest that cannabis causes a decline in testosterone levels by disrupting the production of testosterone. THC has also been shown to inhibit several testicular enzymes needed in testosterone production.
https://www.ncbi.nlm.nih.gov/pubmed/6090909
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thomaskarol