"In the case of a Glioblastoma brain tumor that was removed 99%. Supplementing treatment with CBD and some THC at night. Platelet count is low and not responding to injections. Liver enzyme numbers are also going the wrong way. "
Hello,
I don’t believe cannabis has contributed to the low platelet count. In fact, in a 2014 study, researchers concluded that the endocannabinoid 2-AG stimulated baby blood cells to become platelets (megakaryocytic differentiation). 2-AG, like THC (a phytocannabinoid), binds the cannabinoid-1 (CB1) and cannabinoid-2 receptors (CB2), leading to different physiological reactions, such as lowering inflammation and stimulating platelet formation. However, this study used supraphysiological doses and most likely would not translate to real-world doses of cannabis.
https://www.ncbi.nlm.nih.gov/pubmed/25427281
Additionally, there are several studies which suggest than cannabis increases platelet function, which is why researchers are investigating cannabis’ potential as a treatment for coagulation disorders, such Hemophilia A. However, these studies also involved supraphysiological doses.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190025/#bib9I
I hope this was helpful.
drkim