If you are speaking about a "overdose" of cannabis, there really is no such thing. There has never been a reported death from using cannabis. That being said, the THC content of whatever cannabis product is being used can have psychoactive effects. This, is addition to whatever effects the brain cancer is causing, can show up in different ways depending on the individual as well as the stage of the brain cancer.
A high CBD to THC ratio would probably be the best way to go in this case so as try as minimize the psychoactive effects.
Perry Solomon, MD